A syphilis birth registry match was completed for the first time in Louisiana to identify infants perinatally exposed to syphilis that were missed by routine surveillance activities. The match used a locally-developed, deterministic match and identified 18 potential cases of congenital syphilis. These cases could significantly increase Louisiana congenital syphilis case rate which was the highest in the nation in 2012. The match also identified the need of guidelines for the initiation of congenital syphilis investigations. Other states may wish to conduct a similar birth registry match to ensure complete surveillance for cases of congenital syphilis.
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