Estimation of Basic Reproduction Number of Enterovirus 71, Coxsackievirus A6 and A16 in Hand, Foot, and Mouth Disease Outbreaks in Singapore
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How to Cite

Lim, C., Jiang, L., Ang, L. W., Ma, S., James, L., & Cutter, J. (2014). Estimation of Basic Reproduction Number of Enterovirus 71, Coxsackievirus A6 and A16 in Hand, Foot, and Mouth Disease Outbreaks in Singapore. Online Journal of Public Health Informatics, 6(1). https://doi.org/10.5210/ojphi.v6i1.5091

Abstract

The major enteroviruses causing nationwide epidemics of hand, foot and mouth disease (HFMD) in Singapore were enterovirus 71 (EV71), coxsackievirus A6 (CA6) and A16 (CA16). A mathematical model was used to estimate the basic reproduction number (R<sub>0</sub>) of these enteroviruses based on the cumulative number of reported cases in the initial growth phase of each HFMD outbreak. The median R<sub>0</sub> was estimated to be 3.50 for EV71, 2.42 for CA16, and 5.04 for CA6. The enterovirus-specific R<sub>0</sub> estimates would be helpful in providing insights into the potential growth of future HFMD epidemics for timely implementation of disease control measures.
https://doi.org/10.5210/ojphi.v6i1.5091
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